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Image Search Results
Journal: PLoS ONE
Article Title: Omega-3 fatty acids ameliorate doxorubicin-induced cardiorenal toxicity: In-vivo regulation of oxidative stress, apoptosis and renal Nox4, and in-vitro preservation of the cytotoxic efficacy
doi: 10.1371/journal.pone.0242175
Figure Lengend Snippet: Cardiorenal toxicity were induced in rats by a single intraperioneal injection of doxorubicin (DOX; 200 mg/kg,i.p) after 28 consecutive days of oral administration of omega 3 (OMG; 25, 50 and 100 mg/kg) fatty acids. Forty-eight hours after DOX injection, rats were anesthetized and the electrocardiography (ECG) was recorded for 1 min. (a) showing part of ECG of normal control group (b) showing part of ECG of DOX group with marked bradycardia, elongation of R-R interval, elongation of QTc interval, elevated ST height and depressed T amplitude as compared to normal control group (c) showing part of ECG of DOX+OMG 25 mg/kg group with normalized R-R interval, ST height and elongation of QTc interval (d) showing part of ECG of DOX+OMG 50 mg/kg group with elongated R-R interval and ameliorated of both QTc interval and ST height (e) showing part of ECG of DOX+OMG 100 mg/kg group with elongated R-R interval and bettered of both QTc interval and ST height.
Article Snippet: Subcutaneous peripheral limb electrodes were inserted for
Techniques: Injection, Control
Journal: PLoS ONE
Article Title: Omega-3 fatty acids ameliorate doxorubicin-induced cardiorenal toxicity: In-vivo regulation of oxidative stress, apoptosis and renal Nox4, and in-vitro preservation of the cytotoxic efficacy
doi: 10.1371/journal.pone.0242175
Figure Lengend Snippet: Effect of OMG on R-R interval, heart rate, QRS interval, QTc duration, P duration, ST height and T amplitude of DOX-treated rats.
Article Snippet: Subcutaneous peripheral limb electrodes were inserted for
Techniques: